Targeting Sphingoshine (SP) receptor for Multiple Sclerosis (MS) and P-glycoprotein to discover new anticancer agents for prostate cancer, Multi drug resistant (MDR) cancer
Development of new process for API/KSM and Flow Chemistry
Development of novel inhibitors of Sortase A for attenuating the virulence of Staphylococcus aureus”
Semi-synthesis of Indolizine, Pyrrolo Quinoline/Isoquinoline based natural product hybrids via 1,3-dipolar cycloaddition
N2 Fixation by Heterobimetallic Complexes under Visible Light for the Access of Organonitrogen Compounds as Potential Biological Targets
Live cell fluorescent labelling of Withaferin A targeted protein and their proteomics analysis
Oligonucletide, RNA, DNA and solid phase synthesis eureka
Natural products drug discovery (bioactive natural products)
Extraction, isolation, identification, structural modification (synthesis), bioactivity and mode of action of pharmaceutically important natural products
Bioassay guided approach
Metabolomics of medicinal plants
Development of bioassays for screening plant extracts and isolated compounds
Genome Analysis (transcriptome, proteome, metabolome)
Herb-Drug Pharmacokinetic interaction
Standardization of Phytopharmaceuticals using LC-MS, HPLC
Drug Metabolism of Phytopharmaceuticals
Development of animal models for human diseases such as Diabetes mellitus, Non alcoholic steatohepatitis, inflammatory bowel disease, neurological disorders
Scientific evidence for Indian traditional medicine systems such as Ayurveda, Homoeopathy, Siddha, etc.
Toxicity studies of phtochemicals and synthetic molecules using C. elegans as assay system and rodents
Exosomes as disease markers and drug delivery agents against various cancer models
Gene and protein expression studies
Diabetes and Diabetic complications
Chemotherapy induced Peripheral Neuropathy
Trauma induced Peripheral Neuropathy
Virtual screening of natural compounds and chemical databases against important targets for hit identification
Ligand based pharmacophore mapping
Target based pharmacophore mapping
Molecular dynamic simulation
Electronic structure analysis
Quantum chemical studies of metabolic reaction pathways
Quantum chemical studies of organic reactions (Computation of transition state, energy of reaction, energy of activation)
Machine learning and deep learning approaches
Development of conventional dosage forms including parenteral, biologics for domestic market and later for regulated international markets.
Cater the analytical needs of small scale pharmaceutical industries through its well-developed analytical service facility.
Light activated dual drug delivery systems.
Novel formulations for delivering of drugs to back of the eye .
Microneedles for delivery of biomolecules .